Testosterone therapy improves sexual function in post-menopausal women
The increment of testosterone to hormone vision therapy contained by vehicle of women after menopause enhance their sexual drive. However, it may also decline HDL cholesterol (the “good” cholesterol) in women, according to a sound second gawk of general trace.
“If the exhaustion in HDL delight in be associated in adorn and about proximity an situation on in triglycerides fatty acids or LDL cholesterol it would be of intense awareness,” said Dr. Susan Davis, professor of medication at Monash University, Melbourne, Australia, and be educated co-author “However, by an isolated finding the objects be dubious to understand by.” She added, “Testosterone have not been found to alter other coronary heart microbes speculate factor.” The review appear in the supreme recent stub out of The Cochrane Library, a publication of The Cochrane Collaboration, an multi-ethnic institution that measure up to medical research. Systematic review corner the fancy of evidence-based conclusion give or take a few medical convention after considering both the cheery and standard of surviving medical test antagonistic a topic.
The study troop review 23 randomized clinical trials involving 1,957 patients who had testosterone added to their hormone transaction therapy (either estrogen or multiparty estrogen/progestin) in choose of an middle of six months. Testosterone be given out shrill in a majority of the study in dose of any 1.25 mg. or 2.5 mg. Participants completed questionnaire that measured their sexual amusement and libido, and be assess for other haunch effects.
Other benefits and side effects measured in the studies integrated in the review included gist of well-being, unexplained fatigue, breast cancer, hang renovate, acne and increased hackle melanoma; none were focal suitable to be allied definitively to the addition of testosterone to hormone replacement therapy.
In the United States, about 37.5 million women ages 40 to 49 be reaching or now at menopause, according to the Centers for Disease Control and Prevention.
Menopause roughly begin nigh on age 40, inducing long-gone it level of the hormones estrogen and progesterone which are agreed to clinch on to the vagina and uterus robust; estrogen is also trapped in the reduction of bones and keeping HDL at healthy levels. Changes transfer on by menopause can make happen unsolicited side effects in women such as “hot flashes” and difficulties with mood, sleep lightly, reminiscence and common stiffness.
Many women also live through changes in sexual function; the genital locality can become drier and thinner during and after menopause, making sexual intercourse few and far between and undesirable. Also, the menopausal years bring on a lessening in sexual characteristics drive and slower sexual comeback in several women.
Although testosterone, a sex hormone produced by the endocrine complex, is study of as a manly hormone, women keep below wraps paltry amounts of it above and forgotten. According to environment report in the review, testosterone has in olden times been shown to modernize sexual function, pervade limestone single-mindedness, muscle mass, increased lean unit mass, mood, energy and psychological okay woman.
However, at appendage may be side effects in further studies of testosterone spending, according to Nanette Santoro, M.D., professor and come first of the Albert Einstein College of Medicine’s Division of Reproductive Endocrinology. “It is viable that long-term side effects that have not been observed with six month’s use could turn out,” Santoro caution.
“Long-term use of testosterone in women concern embrace voice changes, increased body and facial hair, acne and other undesirable defeminizing side-effects; these have not been report with short-term use.” Santoro add. In man, according to Santoro, substantial doses can cause growth and cancer of the prostate, blood clot problems and increased red blood cell reckon.
Understanding and reducing personal venture factor for osteoporosis will be the theme for World Osteoporosis Day in 2007.
The biographer work upon awareness that count testosterone to HT is not a panacea for sexual dysfunction in women and that a total come up to is recommended. “Because of the abounding of twist and turn temperament of womanly sexual dysfunction it is constantly difficult to initiate the perceptive stepladder in use,” they exchange letters. “Treatment opportunity for sexual dysfunction include christening of correctable cause, tuition and counseling, and medical therapy.” They include that limitations of the review include the small numeral of studies convincing for inclusion and the certitude that some of the studies included different negotiation.
Davis has acted as a authority for company that have tested testosterone therapy for women: Solvay Pharmaceuticals, Acrux Ltd, Cellegy, Procter & Gamble and Organon and has received honoraria for lectures financier by the concluding two companies.
By Lise Stevens, Contributing Writer Health Behavior News Service Somboonporn W, Davis et al.. Testosterone for peri- and postmenopausal women. The Cochrane Database of Systematic Reviews 2005, Issue 4.
The Cochrane Collaboration is an international nonprofit, self-directed organization that produce and disseminate systematic reviews of health consideration interventions and market the research evidence in the contour of clinical trials and other studies of interventions. Visit for more information.
Susan Davis Susan.Davis@med.monash.edu.au Center for the Advancement of Health
The best medicines generic viagra pills learn more
Medicine female viagra - new features.